Journal Publications



1. LL Wong, ZT Liang, H Chen, ZZ Zhao*. Ingredients authentication of commercial Xihuangcao herbal tea by microscopic technique combined with UPLC-ESI-QTOF-MS/MS. Analytical Methods. 2015, 7(10): 4257-4268

2. Y Jaiswal, ZT Liang, A Ho, HB Chen, ZZ Zhao*. Metabolite profiling of tissues of Acorus calamus and A. tatarinowii rhizomes by using LMD, UHPLC-QTOF MS and GC-MS. Planta Medica. 2015, 81(4): 333-341

3. QL Wang, ZT Liang, Y Peng, JL Hou, SL Wei, ZZ Zhao*, WQ Wang*. Whole transverse section and specific-tissue analysis of secondary metabolites in seven different grades of root of Paeonia lactiflora using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2015, 103: 7-16

4. Yi-Na Tang, Yu-Xin Pang, Xi-Cheng He, Ya-Zhou Zhang, Jian-Ye Zhang, Zhong-Zhen Zhao, Tao Yi*, Hu-Biao Chen*. UPLC–QTOF–MS Identification of Metabolites in Rat Biosamples after Oral Administration of Dioscorea saponins: A Comparative Study. Journal of Ethnopharmacology. 2015; 165:127-140.

5. Jia-Yan Fang, Lin Zhu, Tao Yi*, Jian-Ye Zhang, Ling Yi, Zhi-Tao Liang, Li Xia, Jia-Fu Feng, Jun Xu, Yi-Na Tang, Zhong-Zhen Zhao and Hu-Biao Chen*. Fingerprint analysis of processed Rhizoma Chuanxiong by high -performance liquid chromatography coupled with diode array detection. Chinese Medicine. 2015; 10:2.

6. Tao Yi, Lin Zhu, Wan-Ling Peng, Xi-Cheng He, Hong-Li Chen, Jie Li, Tao Yu, Zhi-Tao Liang, Zhong-Zhen Zhao, Hu-biao Chen*. Comparison of ten major constituents in seven types of processed tea using HPLC-DAD-MS followed by principal component and hierarchical cluster analysis. LWT - Food Science and Technology. 2015; 62(1):194-201.

7. Tian-Bo Zhang, Rui-Qi Yue, Jun Xu, Hing-Man Ho, Dik-Lung Ma, Chung-Hang Leung, Siu-Leung Chau, Zhongzhen Zhao, Hu-Biao Chen*, Quan-Bin Han*. Comprehensive quantitative analysis of Shuang-Huang- Lian oral liquid using UHPLC-Q-TOF-MS and HPLC-ELSD. Journal of Pharmaceutical and Biomedical Analysis. 2015; 102:1-8.

8. Y Ye, XJ Chao, JF Wu, BC Cheng, T Su, XQ Fu, T Li, H Guo, AK Tse, HY Kwan, J Du, GX Chou, ZL Yu*. ERK/GSK3β signaling is involved in atractylenolide I-induced apoptosis and cell cycle arrest in melanoma cells. Oncology Reports. 2015 Jul 6. doi: 10.3892/or.2015.4111.

9. HY Kwan, X Niu, W Dai, T Tong, X Chao, T Su, CL Chan, KC Lee, X Fu, H Yi, H Yu, T Li, AK Tse, WF Fong, SY Pan, A Lu, ZL Yu*. Lipidomic-based investigation into the regulatory effect of Schisandrin B on palmitic acid level in non-alcoholic steatotic livers. Scientific Report. 2015 Mar 13; 5: 9114. doi: 10.1038/srep09114.

10. HY Kwan, X Chao, T Su, XQ Fu, B Liu, AK Tse, WF Fong, ZL Yu*. Dietary lipids and adipocytes: potential therapeutic targets in cancers. The Journal of Nutritional Biochemistry. 2015, 26(4): 303-311



11. ZT Liang*, YJ Chen, L Xu, MJ Qin, T Yi, HB Chen, ZZ Zhao*. Localization of ginsenosides in the rhizome and root of Panax ginseng by laser microdissection and liquid chromatography–quadrupole/time of flight-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2014, 105: 121-133

12. L Yi, ZT Liang, Y Peng, P Guo, LL Wong, XJ Wan, HM Ho, ZZ Zhao*. Histochemical evaluation of alkaloids in rhizome of Coptis chinensis using laser microdissection and liquid chromatography/mass spectrometry. Drug Testing and Analysis. 2014, doi: 10.1002/dta.1703

13. Y Jaiswal, ZT Liang, A Ho, LL Wong, P Yong, HB Chen, ZZ Zhao*. Distribution of toxic alkaloids in the tissues from three herbal medicine Aconitum species using laser micro-dissection, UHPLC-QTOF MS and LC-MS/MS techniques. Phytochemistry. 2014, 107: 155-174   

14. Y Jaiswal, Z Liang, A Ho, P Guo, H Chen, ZZ Zhao*. Tissue-specific metabolite profiling of Cyperus rotundus L. rhizomes and (+)-nootkatone quantitation by using laser micro dissection, UHPLC-QTOF MS and GC-MS techniques. Journal of Food and Agricultural Chemistry. 2014, 62(29): 7302-7316

15. YJ Chen, ZT Liang, Y Zhu, GY Xie, M Tian, ZZ Zhao*, MJ Qin*. Tissue-specific metabolites profiling and quantitative analyses of flavonoids in the rhizome of Belamcanda chinensis by combining laser-microdissection with UHPLC-Q/TOF-MS and UHPLC-QqQ-MS. Talanta. 2014, In press.

16.  XX Huang, ZT Liang, HB Chen, ZZ Zhao*, P Li* (2014). An experimental study on four kinds of Chinese herbal medicines containing alkaloids using fluorescence microscope and microspectrometer. Journal of Microscopy-Oxford. In press.

17. ZT Liang*, KY Oh, YQ Wang, T Yi, HB Chen, ZZ Zhao*. Cell type-specific qualitative and quantitative analysis of saikosaponins in three Bupleurum species using laser microdissection and liquid chromatography–quadrupole/time of flight-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2014, 97:157-165

18. H Xie, JR Wang, LF Yau, Y Liu, L Liu, QB Han, ZZ Zhao*, ZH Jiang*. Catechins and procyanidins of Ginkgo biloba show potent activities towards the inhibition of β-amyloid peptide aggregation and destabilization of preformed fibrils. Molecules. 2014, 19(4): 5119-5134.

19. H Xie, JR Wang, LF Yau, Y Liu, L Liu, QB Han, ZZ Zhao*, ZH Jiang*. Quantitative analysis of the flavonoid glycosides and terpene trilactones in the extract of Ginkgo biloba and evaluation of their inhibitory activity towards fibril formation of β-amyloid peptide. Molecules. 2014, 19(4): 4466-4478.

20. Y Jaiswal, ZT Liang, A Ho, HB Chen, ZZ Zhao*. A comparative tissue specific metabolite analysis and determination of protodioscin content in Asparagus species used in Traditional Chinese Medicine and Ayurveda by use of laser micro dissection, UHPLC-QTOF MS and LC-MS/MS techniques. Phytochemical Analysis. 2014 Apr 16. doi: 10.1002/pca.2522.

21. MH Wu, W Zhang, P Guo, ZZ Zhao*. Identification of seven Zingiberaceous species based on comparative anatomy of microscopic characteristics of seeds. Chinese Medicine. 2014, 9(1):10

22. Tao Yi, Shuk-Man Li, Jia-Yi Fan, Lan-Lan Fan, Zhi-Feng Zhang, Pei Luo, Xiao-Jun Zhang, Jian-Gang Wang, Lin Zhu, Zhong-Zhen Zhao and Hu-Biao Chen*. Comparative analysis of EPA and DHA in fish oil nutritional capsules by GC-MS. Lipids in Health and Disease. 2014; 13:190.

23. Jun Xu, Song-Lin Li, Rui-Qi Yue, Chun-Hay Ko, Jiang-Miao Hu, Jing Liu, Hing-Man Ho, Tao Yi, Zhong-Zhen Zhao, Jun Zhou, Ping-Chung Leung, Hu-Biao Chen*, Quan-Bin Han*. A novel and rapid HPGPC-based strategy for quality control of saccharide-dominant herbal materials: Dendrobium officinale, a case study. Analytical and Bioanalytical Chemistry. 2014; 406(25):6409-6417.

24. Ya-Zhou Zhang, Feng Xu, Jian-Ye Zhang, Tao Yi, Yi-Na Tang, Jun Xu, Wan-Ling Peng, Hu-Biao Chen*. The analysis of the fragmentation behaviors of 11 isoflavones with ESI-IT-TOF-MSn. Journal of Chinese Pharmaceutical Sciences. 2014; 23(9):631-641.

25. Shuk-Ching Tze, Zhong-Zhen Zhao, Hu-Biao Chen*, Statistical analysis of Chinese herbal medicines commonly used in Hong Kong Chinese medicine clinics. Hong Kong Chinese Medicinal Journal. 2014; 9(3):43-47. (in Chinese)

26. Tao Yi, Lan-Lan Fan, Hong-Li Chen, Guo-Yuan Zhu, Hau-Man Suen, Yi-Na Tang, Lin Zhu, Zhongzhen Zhao, Hubiao Chen*, Comparative analysis of diosgenin in Dioscorea species and related medicinal plants by UPLC-DAD-MS. BMC Biochemistry. 2014; 15:19.

27. Jia-Yi Fan, Tao Yi *, Chui-Mei Sze-To, Lin Zhu, Wan-Ling Peng, Ya-Zhou Zhang, Zhong-Zhen Zhao and Hu-Biao Chen*. A Systematic Review of the Botanical, Phytochemical and Pharmacological Profile of Dracaena cochinchinensis, a Plant Source of the Ethnomedicine “Dragon’s Blood”. Molecules. 2014; 19:10650-10669.

28. Qilei Chen, Tao Yi*, Yina Tang, Lailai Wong, Xiaoxuan Huang, Zhongzhen Zhao, and Hubiao Chen*. Comparative authentication of three “Snow Lotus” herbs by macroscopic and microscopic features. Microscopy Research and Technique. 2014; 77:631-641.

29. Guangyi Yang, Hubiao Chen*, Zhongzhen Zhao, Tao Yi, Jiyan Chen. Resources and utilization of Taoist Medicinal Plants Distributed in Wudang Mountain. Journal of Chinese Pharmaceutical Sciences. 2014; 23(6):412-420.

30. Tao Yi, Lin Zhu, Yi-Na Tang, Jian-Ye Zhang, Zhi-Tao Liang, Jun Xu, Zhong-Zhen Zhao, Zhi-Ling Yu, Zhao-Xiang Bian, Zhi-Jun Yang, Hu-biao Chen*. An integrated strategy based on UPLC–DAD–QTOF-MS for metabolism and pharmacokinetic studies of herbal medicines: Tibetan “Snow Lotus” herb (Saussurea laniceps), a case study. Journal of Ethnopharmacology. 2014;153 (3) :701-713.

31. Zhang Yazhou, Xu Feng, Yi Tao, Zhang Jianye, Xu Jun, Tang Yinna, He Xichen, Liu Jing, Chen Hubiao*. Chemical profile analysis and comparison of two versions of the classic TCM formula Danggui Buxue Tang by HPLC-DAD-ESI-IT-TOF-MSn. Molecules. 2014; 19:5650-5673.

32. Jun Xu, Rui-Qi Yue, Jing Liu, Hing-Man Ho, Tao Yi, Hu-Biao Chen*, Quan-Bin Han*. Structural diversity requires individual optimization of ethanol concentration in polysaccharide precipitation. International Journal of Biological Macromolecules. 2014; 67:205-209.

33. Yina Tang, Xichen He, Quanlan Chen, Lanlan Fan, Jianye Zhang, Zhongzhen Zhao,Lisha Dong, Zhitao Liang, Tao Yi*, and Hubiao Chen*. A Mixed Microscopic Method for Differentiating Seven Species of “Bixie”- Related Chinese Materia Medica. Microscopy Research and Technique. 2014; 77:57-70.

34. Kun-Zi Yu, Jing Liu, Bao-Lin Guo, Zhong-Zhen Zhao, Hao Hong, Hu-Biao Chen*, Shao-Qing Cai*. Microscopic research of a multi-source traditional Chinese medicine: Asdragli Radix. Journal of Natural Medicines. 2014; 68(2):340-50.

35. T Su, H Yu, HY Kwan, XQ Ma, HH Cao, CY Cheng, AK Leung, CL Chan, WD Li, H Cao, WF Fong, ZL Yu*. Comparisons of the chemical profiles, cytotoxicities and anti-inflammatory effects of raw and rice wine-processed Herba Siegesbeckiae. Journal of Ethnopharmacology. 2014, 156: 365-369

36. XQ Ma, AK Leung, CL Chan, T Su, WD Li, SM Li, DW Fong, ZL Yu*. UHPLC UHD Q-TOF MS/MS analysis of the impact of sulfur fumigation on the chemical profile of Codonopsis Radix (Dangshen). Analyst. 2014, 39(2): 505-516.




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